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KMID : 0387920070180020161
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Korean Journal of Cytopathology
2007 Volume.18 No. 2 p.161 ~ p.164
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Metastatic Melanoma Mimicking a Papillary Carcinoma of the Thyroid in Fine Needle Aspiration Cytology -A Case Report-
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Hong Young-Ok
Suh Jae-Hee
Cha Hee-Jung
Choi Hye-Jeong
Kim Young-Min
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Abstract
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Metastasis to the thyroid gland is very rare in clinical practice. We recently encountered a 65-year-old woman who presented with a large thyroid nodule that mimicked the cytologic features of a papillary thyroid carcinoma on fine needle aspiration biopsy (FNAB). Although initially diagnosed as a papillary thyroid carcinoma, a thorough clinical work-up revealed multiple lesions in the bones, liver, and nasal cavity, which were confirmed as metastases of a malignant melanoma. Despite a thorough physical examination, however, the primary skin lesion could not be identified. Although FNAB shows a high degree of accuracy in diagnosing primary thyroid tumors, it is less accurate in diagnosing metastases to the thyroid gland. A thorough clinical history with appropriate immunohistochemical staining assays is necessary for the accurate diagnosis of metastatic malignant melanoma.
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KEYWORD
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Malignant melanoma, Thyroid gland, Metastasis
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